Diomy Milanes Cytologist. In 1993 painted cytologic cellular changes in Pap smears from feminine reproductive system

Atypical Cellular Changes

From

Feminine Genital Tract

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Coccoid Bacterial Infection

In this painting large amount of micro coccus are covering part of the squamous superficial cells. It is a berry-shaped microorganism, related to or resembling a coccus which is a spherical bacterium.

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Gardenella vaginalis or Heamophilus vaginalis

In this microscopic view the painting shows the squamous superficial cells almost covered by the bacteria. It can be transmitted by sexual contact with an infected person.

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Leptothrix

The Cytologist, in this painting, shows the variation in size of the bacteria. It sometimes cannot be differentiated from Lactobacillus, often these bacteria are composed of long non branching filamentous rods and many times trichomonas are associated with this infestation.

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Trichomonas vaginalis

In this microscopic view we are looking at very small grayish-green, pear-shaped protozoa. Eosinophilic granules are often seen in their cytoplasm. A nucleus must be identified in order to render a diagnostic of "trich". The squamous epithelial cells shows perinuclear halos and enlargement of the cells. Many white blood cells are present.

5.- Monila or Candida Albicans Click to enlarge
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Monilias or Candida albicans

In this painting we can see the fungus most frequently found in Pap smears. Segmented branching hyphen and yeast fungus. Sometimes you only see yeast forms.The squamous epithelial cells do not shows distortion, the smear is very clear no white blood cells are present.

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Monilias and Trichomonads

In this microscopic view there are both infestation present in the smear, the smear is clean.

7.- Herpes simplex Click to enlarge
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Herpes simplex

In this painting the Cytologist shows the inclusion bodies characteristic of the most widely recognized viral infection of the female genital tract.

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Human papilloma virus (HPV1)

This painting is one of the most dramatic in appearance, because the presence of koilocytes (koilos means "hollow" in greek) that is pathogenic of HPV1 infection.

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Human papilloma virus (HPV2)

The Cytologist in this painting. had a microscopic view showing many dyskeratocytes which are the second cells type in HPV infection, they are small keratinized cells with piknotic nuclei, found in sheets and clusters. These cellular changes are clue to correct diagnosis of HPV2.

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Chlamydia tracomatis

In my last painting showing the Chlamydia infection, the infectious elementary bodies enter metaplastic cells, endocervical cells. The atypical cellular changes are in the cytoplasm, cellular and nuclear enlargement, with large vacuoles containing the inclusion bodies.

Last Updated March 17 2010

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